This doesn't sound good no matter what the motives were:

SEATTLE – At least two people have been shot at the Jewish Federation at 2031 Third Ave. in downtown Seattle. One or two people have been taken into custody but it’s not known if they are suspects.

One person was reportedly shot in the abdomen and another in the arm. They are being taken to Harborview Medical Center.

Part of Third Avenue has been closed to traffic. Police are urging people to stay away from the area. It’s not known if more suspects are at large but policemen were seen handcuffing one person and others were searching the area.

At least three people were seen emerging from the building, escorted by police. It’s not know if they were hostages.

Medics have been taking other people from the building.

Details appear to be sketchy; Charles Johnson asks if it's "Possibly related to the Hizballah war". Even if it isn't, Hugh Hewitt is spot-on when he writes, "The import of this is clear: All Jewish centers and synagogues need to be on high, high alert asap".

Update: The Seattle NBC affiliate King5 is now reporting that three have been shot, all women.

Another Update: The King5 article is being updated in real time as new details come in. They're now listing four victims, one of whom has died. They add that "Police have taken one person into custody but there may be more suspects in or around the building".

More: Michelle Malkin quotes the Seattle P-I:

One witness, who declined to give her name, said a man walked into the Jewish Federation building with a gun, said he was upset about what was going on in Israel, then opened fire. After the shootings, the man said to call 911, the witness said. The witness said the man identified himself as an American Muslim.

I'm astonished that someone could become radicalized in Seattle, where social services are so plentiful. I'm sure others will share in my incomprehension.

Related: This lengthy post by Austin Bay compares modern-day Islamofascism with the frequently violent anarchy movement of the turn of the 20th century. Be sure to read the comments as well.